Wegovy (Semaglutide) - Key Facts
1. What is Wegovy?
- Wegovy is a prescription medication developed by Novo Nordisk for weight management in adults.
- It contains semaglutide, a GLP-1 (glucagon-like peptide-1) receptor agonist.
2. How Does Wegovy Work?
- Wegovy mimics the action of the GLP-1 hormone, which helps regulate appetite, food intake, and insulin release.
- It reduces hunger and increases feelings of fullness, helping people eat less and make healthier food choices.
- It also slows gastric emptying, which can contribute to sustained feelings of satiety after meals.
3. Who Can Use Wegovy?
- Approved for adults with obesity (BMI ≥ 30) or overweight (BMI ≥ 27) with at least one weight-related health condition, such as type 2 diabetes, hypertension, or high cholesterol.
- Not recommended for people with a history of medullary thyroid cancer or multiple endocrine neoplasia type 2(MEN 2).
4. Administration
- Wegovy is administered as a weekly subcutaneous injection (under the skin) using a pre-filled pen.
- The dose starts low and is gradually increased over several weeks to reduce side effects and allow the body to adjust.
5. Effectiveness
- Clinical studies have shown that Wegovy can help individuals lose 15% to 20% of their body weight on average when combined with a reduced-calorie diet and increased physical activity.
- Results may vary, but significant weight loss can be sustained over long periods with continued use.
6. Side Effects
- Common side effects include nausea, diarrhea, constipation, abdominal pain, and headache.
- Most side effects tend to decrease over time as the body adjusts to the medication.
- Serious side effects (though rare) may include pancreatitis, gallbladder problems, and kidney issues.
7. Safety Considerations
- Wegovy should be used alongside a healthy diet and exercise program to achieve the best results.
- Regular monitoring by a healthcare provider is essential to manage side effects and track progress.
- Not suitable for those with certain medical conditions, such as pregnancy or serious gastrointestinal disorders.
8. Long-Term Use
- Wegovy is typically used as a long-term treatment for weight loss, as discontinuing the medication can result in regaining lost weight.
- Continuing a healthy lifestyle with diet and exercise can help maintain weight loss even after stopping the medication.
9. Availability
- Wegovy is available by prescription in many countries, including the US, UK, and EU.
- It's important to discuss with a healthcare provider if Wegovy is the right treatment option based on individual health needs and goals.
10. Additional Benefits
- Besides aiding in weight loss, Wegovy has been shown to improve blood sugar control in individuals with type 2 diabetes and has beneficial effects on cardiovascular health, including reducing the risk of major heart events.
Wegovy represents a powerful tool in weight management, especially for those struggling with obesity or overweight-related health conditions. However, it’s important to use it as part of a comprehensive lifestyle approach under the guidance of a healthcare provider.
Full information can be found on the Wegovy fact sheet here.